【摘要】：目的 調(diào)查天津市靜海農(nóng)村地區(qū)10歲至15歲學(xué)齡期兒童代謝綜合征(MS)的患病情況,探討兒童MS與肥胖、代謝異常及與各組分的關(guān)系,為兒童青少年肥胖及MS早期干預(yù)提供可靠的依據(jù)。 方法 根據(jù)分層整群隨機抽樣的原則對靜海農(nóng)村地區(qū)2596名10歲至15歲學(xué)生進行體檢,測定腰圍、身高、體重、血壓、血糖、甘油三酯、膽固醇、高密度脂蛋白、低密度脂蛋白、血尿酸。根據(jù)BMI法篩選出超重、肥胖和正常體重兒童,了解不同組別MS及所監(jiān)測代謝指標(biāo)異常情況。 結(jié)果 1.本研究提示天津市靜海農(nóng)村地區(qū)學(xué)齡期兒童MS患病人數(shù)比例較高,應(yīng)引起人們的關(guān)注,共檢出代謝綜合征81例,男生49名,女生32名,總檢出率為3.12%,肥胖與超重學(xué)齡兒童中MS發(fā)病人數(shù)81例,檢出率為14.70%。 2.依據(jù)BMI劃分肥胖組、超重組與正常組,天津市靜海農(nóng)村地區(qū)2596名10歲至15歲兒童超重檢出率為12.71%,肥胖檢出率為8.51%,其中男生的超重者為14.11%,肥胖者為9.15%,女生超重為11.28%,肥胖為7.86%,男生明顯高于女生,p0.05。 3.肥胖組與超重組及正常組比較,TG、TC、HDL-C、LDL-C均存在顯著差異,p0.05；各年齡組兒童血脂異常者共284人,總檢出率為10.94%,其中TG水平升高者160例(6.16%),TC水平升高者143例(5.51%),HDL-C (?)(?)低者141例(5.43%),LDL-C水平升高者73例(2.81%),TG水平隨年齡增長有升高趨勢,而HDL-C水平隨年齡增長有降低趨勢。 4.按性別分組,男生與女生TC、LDL-C、HDL-C、GLU、BMI均存在顯著的差異,其中男生的TC、LDL-C、HDL-C均低于女生,而GLU、BMI均高于女生,男生與女生TG差異無統(tǒng)計學(xué)意義,(p0.05)。 5.高尿酸血癥311例,占總?cè)藬?shù)的11.59%,男生高尿酸血癥檢出率明顯高于女生,女生為4.82%,男生18.99%,二者比較差異具有統(tǒng)計學(xué)意義(p0.05)；高尿酸血癥組與尿酸正常組比較,BMI、腰圍、血壓均明顯增高,血尿酸水平與年齡、腰圍、BMI、血壓均呈正相關(guān)。 結(jié)論 1.通過在較大樣本兒童青少年人群中的調(diào)查,報道天津市靜海農(nóng)村地區(qū)兒童青少年代謝綜合征及其組分異常檢出率,本研究結(jié)果提示本地區(qū)肥胖兒童已具有較高的代謝綜合征患病率。 2.本研究顯示腹型肥胖、高甘油三酯血癥及高血壓是發(fā)生率最高的代謝綜合征成分。 3.靜海農(nóng)村地區(qū)兒童中約3.12%患有代謝綜合征,已經(jīng)出現(xiàn)腹型肥胖、血脂異常、高血壓等心血管疾病主要危險因素。兒童超重和肥胖與代謝綜合征及其代謝異常組份密切相關(guān),隨著兒童體重增加,兒童發(fā)生代謝綜合征及其代謝異常組份風(fēng)險明顯增加。
[Abstract]:Purpose To investigate the prevalence of metabolic syndrome (MS) of children between the ages of 10 and 15 in the rural areas of the Jinghai, Tianjin, and to study the relationship between the children's MS and obesity, the abnormal metabolism and the relationship with the components, and to provide a reliable basis for the early intervention of the children's obesity and the early intervention of the MS. It was reported. Methods According to the principle of stratified cluster random sampling,2596 students from 10 to 15 years of age in the rural area of Jinghai were examined, and the waist, height, body weight, blood pressure, blood sugar, triglyceride, cholesterol, high density lipoprotein and low density fat were measured. White and blood uric acid. Overweight, obese and normal weight children were selected according to the BMI method to understand the MS and the monitored metabolic finger in different groups. to be different from one another Results 1. The results of this study suggest that the proportion of MS of children in the rural areas in the rural area of Tianjin is high, and the attention of the people should be caused. Among them, there are 81 cases of metabolic syndrome,49 male and 32 female students. The total detection rate is 3.12%, and the obesity and overweight school-age children The number of MS in 81 cases, the test The prevalence of overweight was 14.70%.2. The prevalence of overweight was 12.71%, the prevalence of obesity was 8.51%, the overweight of boys was 14.11%, the rate of obesity was 9.15%, and the overweight was 11.2%. 8%, obesity 7.86%, boys There was a significant difference in TG, TC, HDL-C and LDL-C in the obese group compared with that in the normal group. The total positive rate of TG, TC, HDL-C and LDL-C was 10.94%. Among them, there were 160 cases (6.16%) of TG level and 143 cases (6.16%) of TC. 5.5 1 (%), while HDL-C (?) (?) (?) (?) (?) (?) (?) (?)? (?)? (?)? 4. The levels of TC, LDL-C and HDL-C in male and female were lower than that of female, while GLU and BMI were higher than that of girls. 5. There were 311 cases of hyperuricemia, 11.59% of the total, and the rate of hyperuricemia in boys was significantly higher than that of female students (4.82%) and the male (18.99%), and the difference of the two was statistically significant (p0.05); hyperuricemia Compared with the normal group of uric acid, BMI, waist circumference and blood pressure were significantly higher, and the level of uric acid was higher than that in the normal group of uric acid. age Conclusion 1. The prevalence of metabolic syndrome and its components in children and adolescents in the rural areas of Tianjin are reported. Obese children in the region have a high prevalence of metabolic syndrome.2. The study shows that abdominal obesity, Gump, Oil triester and hypertension are the highest rate of metabolic syndrome.3. About 3.12% of children in the rural areas of the static sea have a metabolic syndrome, which has occurred. The main risk factors of the cardiovascular diseases such as abdominal obesity, dyslipidemia, hypertension, etc. The overweight and obesity of children are closely related to the metabolic syndrome and its metabolic abnormal components, and with the increase of the weight of the children
【學(xué)位授予單位】：天津醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R725.8

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